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13 Cruises

New Ship

12 Nights South America Cruise

Duration

12 Nights

Ship

AmaMelodia

Port of Call

Medellin - Medellin - Medellin - Cartagena Turistica - Cartagena Turistica - Cartagena Turistica - Manzini - Calamar - Magangue - Mompox - Mompox - Mompox - Caransebes - Barranquilla - BarranquillaItinerary Details

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Itinerary Details

12 Nights South America Cruise

Avg. per person

From

$5,949

as little as

$496/night

What's Included?

*Prices shown are per person and include all taxes and fees.

Duration

12 Nights

Ship

AmaMelodia

Port of Call

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Itinerary Details

Avg. per person

From

$5,949

as little as

$496/night

*Prices shown are per person and include all taxes and fees.

What's Included?

Oct 2, 2026 - Oct 14, 2026 Fri - Wed

Interior

Oceanview

Balcony

Suite

Oct 2, 2026 - Oct 14, 2026 Fri - Wed

Bonus Details

$6,099 USD

$7,698 USD

Select

Bonus Details

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All the Cruise Line Offers & More

Oct 30, 2026 - Nov 11, 2026 Fri - Wed

Bonus Details

$6,099 USD

$7,698 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Travel Weekly Award - Best Cuisine

12 Nights South America Cruise

Duration

12 Nights

Ship

AmaMagdalena

Port of Call

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Itinerary Details

12 Nights South America Cruise

Sold Out

What's Included?

*Prices shown are per person and include all taxes and fees.

Duration

12 Nights

Ship

AmaMagdalena

Port of Call

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Itinerary Details

Sold Out

*Prices shown are per person and include all taxes and fees.

What's Included?

Oct 5, 2026 - Oct 17, 2026 Mon - Sat

Interior

Oceanview

Balcony

Suite

Oct 5, 2026 - Oct 17, 2026 Mon - Sat

Bonus Details

$6,099 USD

$8,098 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 19, 2026 - Oct 31, 2026 Mon - Sat

Bonus Details

$6,099 USD

$8,098 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

USA Today Best Cruise Line

10 Nights South America Cruise

Duration

10 Nights

Ship

Delfin III

Port of Call

Lima, Peru - Lima - Sacred Valley - Sacred Valley - Machu Picchu - Cusco - Cusco-lima-iquitos-nauta-peruvian Amazon River (embarkation) - Peruvian Amazon - Peruvian Amazon - Iquitos (disembarkation) - LimaItinerary Details

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Wedding

Yacht & Expedition Cruises

Itinerary Details

10 Nights South America Cruise

Avg. per person

From

$7,058

as little as

$706/night

What's Included?

*Prices shown are per person and include all taxes and fees.

Duration

10 Nights

Ship

Delfin III

Port of Call

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Wedding

Yacht & Expedition Cruises

Itinerary Details

Avg. per person

From

$7,058

as little as

$706/night

*Prices shown are per person and include all taxes and fees.

What's Included?

Oct 4, 2026 - Oct 14, 2026 Sun - Wed

Interior

Oceanview

Balcony

Suite

Oct 4, 2026 - Oct 14, 2026 Sun - Wed

Bonus Details

$7,308 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 11, 2026 - Oct 21, 2026 Sun - Wed

Bonus Details

$7,108 USD

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Bonus Details

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All the Cruise Line Offers & More

Oct 18, 2026 - Oct 28, 2026 Sun - Wed

Bonus Details

$7,108 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 25, 2026 - Nov 4, 2026 Sun - Wed

Bonus Details

$7,108 USD

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Bonus Details

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All the Cruise Line Offers & More

USA Today Best Cruise Line

12 Nights South America Cruise

Duration

12 Nights

Ship

Delfin III

Port of Call

Arrive In Lima, Peru - Lima-pisco-paracas & Nazca Lines - Paracas-ballestas Island Cruise-lima - Lima - Sacred Valley - Sacred Valley - Machu Picchu - Cusco - Cusco-lima-iquitos-nauta-peruvian Amazon River (embarkation) - Peruvian Amazon - Peruvian Amazon - Iquitos (disembarkation) - LimaItinerary Details

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Wedding

Yacht & Expedition Cruises

Itinerary Details

12 Nights South America Cruise

Avg. per person

From

$8,258

as little as

$688/night

What's Included?

*Prices shown are per person and include all taxes and fees.

Duration

12 Nights

Ship

Delfin III

Port of Call

Best For

Gourmet

River Cruises

Honeymoon

Luxury

Romantic

Senior

Wedding

Yacht & Expedition Cruises

Itinerary Details

Avg. per person

From

$8,258

as little as

$688/night

*Prices shown are per person and include all taxes and fees.

What's Included?

Oct 2, 2026 - Oct 14, 2026 Fri - Wed

Interior

Oceanview

Balcony

Suite

Oct 2, 2026 - Oct 14, 2026 Fri - Wed

Bonus Details

$8,508 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 9, 2026 - Oct 21, 2026 Fri - Wed

Bonus Details

$8,308 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 16, 2026 - Oct 28, 2026 Fri - Wed

Bonus Details

$8,308 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 23, 2026 - Nov 4, 2026 Fri - Wed

Bonus Details

$8,308 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Oct 30, 2026 - Nov 11, 2026 Fri - Wed

Bonus Details

$8,308 USD

Select

Bonus Details

Select

All the Cruise Line Offers & More

Filter Cruises

13 Cruises

12 Nights South America Cruise

12 Nights South America Cruise

DO YOU HAVE A FUTURE CRUISE CREDIT? Redeem your future cruise credit with CruiseDirector. Call us today 1-888-409-2784.

12 Nights South America Cruise

12 Nights South America Cruise

JOIN THE VOYAGER CLUB! Members receive Airport Club Access, Concierge Support, Price Assurance & More.

10 Nights South America Cruise

10 Nights South America Cruise

MAKE THE WORLD GREENER CruiseDirector and One Tree Planted are planting a tree for every passenger who sails with us.

12 Nights South America Cruise

12 Nights South America Cruise

BEST PRICE GUARANTEE! If you find a lower price online, we’ll match it!

DO YOU HAVE A FUTURE CRUISE CREDIT?

Redeem your future cruise credit with CruiseDirector. Call us today 1-888-409-2784.

JOIN THE VOYAGER CLUB!

Members receive Airport Club Access, Concierge Support, Price Assurance & More.

MAKE THE WORLD GREENER

CruiseDirector and One Tree Planted are planting a tree for every passenger who sails with us.

BEST PRICE GUARANTEE!

If you find a lower price online, we’ll match it!